主要学术成绩:近年来在国内外核心刊物上以第一作者或通讯作者发表SCI论文19篇;主持国家自然科学基金2项(81673442,81202974),江苏省自然科学基金1项(BK2011625),“天然药物活性组分与药效”国家重点实验室(中国药科大学)优秀青年学者基金项目(JKGQ201108),中央高校基本科研业务费专项资金(JKQ2009019,JKPZ2013018)。作为药理负责人参加多项国家及省级课题,并负责多项抗心脑缺血新药的药理毒理研究工作。
代表性文章(5篇):
1. Fang W, Sha L, Kodithuwakku ND, Wei J, Zhang R, Han D, Mao L, Li Y. Attenuated Blood-Brain Barrier Dysfunction by XQ-1H Following Ischemic Stroke in Hyperlipidemic Rats. Mol Neurobiol. 2015; 52(1): 162-75. (SCI,IF: 5.397)
2. Han D, Fang W, Zhang R, Wei J, Kodithuwakku ND, Sha L, Ma W1, Liu L, Li F, Li Y. Clematichinenoside protects blood brain barrier against ischemic stroke superimposed on systemic inflammatory challenges through up-regulating A20. Brain Behav Immun. 2016; 51: 56-69. (SCI,共同第一作者,IF: 5.874)
3. Fang W, Zhang R, Sha L, Lv P, Shang E, Han D, Wei J, Geng X, Yang Q, Li Y. Platelet activating factor induces transient blood-brain barrier opening to facilitate edaravone penetration into the brain. J Neurochem. 2014; 128(5): 662-71. (SCI,IF:4.281)
4. Huang J, Kodithuwakku ND, He W, Zhou Y, Fan W, Fang W, He G, Wu Q, Chu S, Li Y. The neuroprotective effect of a novel agent N2 on rat cerebral ischemia associated with the activation of PI3K/Akt signaling pathway. Neuropharmacology. 2015; 95: 12-21. (SCI,共同通讯作者,IF:4.936)
5. Fang W, Deng Y, Li Y, Shang E, Fang F, Lv P, Bai L, Qi Y, Yan F, Mao L. Blood brain barrier permeability and therapeutic time window of Ginkgolide B in ischemia-reperfusion injury. Eur J Pharm Sci. 2010; 39 (1-3): 8-14. (SCI,IF:3.512)
著作:
1. 李运曼,方伟蓉主编. 《心血管药理学》. 江苏科技出版社. 2014年3月
2. 吴玉林,颜天华主编,方伟蓉副主编. 《人体解剖生理学》. 东南大学出版社. 2012年7月